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Index > Protein center > VDAC2(Gene name) > Human
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  • VDAC2 (Gene name),
  • Voltage-dependent anion-selective channel protein 2 (Protein name ),  VDAC2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    VDAC2;
    Protein name:
    Voltage-dependent anion-selective channel protein 2(VDAC-2;hVDAC2);
    Alternative:
    Outer mitochondrial membrane protein porin 2;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with hexokinases.
    Function:
    Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective.
    Subcellular Location:
    Mitochondrion outer membrane
    Protein Attributes:
    Sequence length:
    294
    Sequence:
    50:
    MATHGQTCAR | PMCIPPSYAD | LGKAARDIFN | KGFGFGLVKL | DVKTKSCSGV | 
    100:
    EFSTSGSSNT | DTGKVTGTLE | TKYKWCEYGL | TFTEKWNTDN | TLGTEIAIED | 
    150:
    QICQGLKLTF | DTTFSPNTGK | KSGKIKSSYK | RECINLGCDV | DFDFAGPAIH | 
    200:
    GSAVFGYEGW | LAGYQMTFDS | AKSKLTRNNF | AVGYRTGDFQ | LHTNVNDGTE | 
    250:
    FGGSIYQKVC | EDLDTSVNLA | WTSGTNCTRF | GIAAKYQLDP | TASISAKVNN | 
    294:
    SSLIGVGYTQ | TLRPGVKLTL | SALVDGKSIN | AGGHKVGLAL | ELEA
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    Pfam:
    KEGG:
    SMR:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human VDAC-2
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    E12943r
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    ELISA Kit for Human VDAC-2
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    E12943m
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    ELISA Kit for Human VDAC-2
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    E12943h
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    ELISA Kit for Human VDAC-2
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    E12943p
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    ELISA Kit for Human VDAC-2
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    E12943b
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    ELISA Kit for Human VDAC-2
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    CLIA Kit for Human VDAC-2
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    U12943m
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    Packing:
    96T
    CLIA Kit for Human VDAC-2
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    CLIA Kit for Human VDAC-2
    Cat.:
    U12943r
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    Packing:
    96T
    CLIA Kit for Human VDAC-2
    Cat.:
    U12943h
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    96T
    CLIA Kit for Human VDAC-2
    Cat.:
    U12943b
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    96T
    CLIA Kit for Human VDAC-2
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    U12943p
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    Packing:
    96T
    Polyclonal Antibody for Human VDAC-2
    Cat.:
    P12943Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human VDAC-2
    Polyclonal Antibody for Human VDAC-2
    Polyclonal Antibody for Human VDAC-2
    Polyclonal Antibody for Human VDAC-2
    Cat.:
    P12943Rb-r
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    Packing:
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    Polyclonal Antibody for Human VDAC-2
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    P12943Rb-m
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human VDAC-2
    Monoclonal Antibody for Human VDAC-2
    Monoclonal Antibody for Human VDAC-2
    Monoclonal Antibody for Human VDAC-2
    Monoclonal Antibody for Human VDAC-2
    Monoclonal Antibody for Human VDAC-2
    Protein for Human VDAC-2
    Protein for Human VDAC-2
    Protein for Human VDAC-2
    Protein for Human VDAC-2
    Protein for Human VDAC-2
    Protein for Human VDAC-2

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    References
    1. 1.
      "A mitochondrial porin cDNA predicts the existence of multiple human porins."
      Ha H. , Hajek P. , Bedwell D.M. , Burrows P.D.
      J. Biol. Chem.268:12143-12149(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
      tissue: B-cell.
    2. 2.
      "Cloning and functional expression in yeast of two human isoforms of the outer mitochondrial membrane channel, the voltage-dependent anion channel."
      Blachly-Dyson E. , Zambronicz E.B. , Yu W.H. , Adams V. , McCabe E.R. , Adelman J.P. , Colombini M. , Forte M.A.
      J. Biol. Chem.268:1835-1841(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);VARIANT VAL-24
      tissue: Liver.
    3. 3.
      "Revised fine mapping of the human voltage-dependent anion channel loci by radiation hybrid analysis."
      Decker W.K. , Bowles K.R. , Schatte E.C. , Towbin J.A. , Craigen W.J.
      Mamm. Genome10:1041-1042(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 3)
    4. 4.
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      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    5. 5.
      "The DNA sequence and comparative analysis of human chromosome 10."
      Deloukas P. , Earthrowl M.E. , Grafham D.V. , Rubenfield M. , French L. , Steward C.A. , Sims S.K. , Jones M.C. , Searle S. , Scott C. , Howe K. , Hunt S.E. , Andrews T.D. , Gilbert J.G.R. , Swarbreck D. , Ashurst J.L. , Taylor A. , Battles J. , more...
      Nature429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      tissue: Cervix.
      tissue: Eye.
    7. 7.
      Lubec G. , Vishwanath V. , Chen W.-Q. , Sun Y.
      Submitted (2008-12) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 86-120; 178-229 AND 248-267;IDENTIFICATION BY IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Brain.
      tissue: Cajal-Retzius cell.
      tissue: Fetal brain cortex.
    8. 8.
      Bienvenut W.V.
      Submitted (2005-06) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 11-23 (ISOFORM 3);PROTEIN SEQUENCE OF 46-64; 75-85; 108-120; 178-185; 236-263 AND 268-277 (ISOFORMS 1/2/3);IDENTIFICATION BY MASS SPECTROMETRY
      tissue: B-cell lymphoma.
    9. 9.
      "Subcellular localization of human voltage-dependent anion channel isoforms."
      Yu W.H. , Wolfgang W. , Forte M.A.
      J. Biol. Chem.270:13998-14006(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    10. 10.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Platelet.
    12. 12.
      "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
      Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
      Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    14. 14.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
    15. 15.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-31;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    16. 16.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    17. 17.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    18. 18.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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